WAY208466 dihydrochloride( —— )

Catalog No. M33948 CAS No. 1207064-61-6

WAY208466 dihydrochloride is a selective and potent 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity, which can be used for the study of neurological disorders such as depression and anxiety.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

WAY208466 dihydrochloride
Note

Research use only, not for human use.
Brief Description

WAY208466 dihydrochloride is a selective and potent 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity, which can be used for the study of neurological disorders such as depression and anxiety.
Description

WAY 208466 dihydrochloride is a potent and selective 5-HT6 receptor agonist (EC50=7.3 nM for the human 5-HT6 receptor). WAY-208466 dihydrochloride elevates cortical GABA levels in rat frontal cortex. WAY 208466 dihydrochloride exhibits antidepressant and anxiolytic-like effects.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

1207064-61-6
Formula Weight

420.33
Molecular Formula

C17H20Cl2FN3O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

O=S(C1=CC(F)=CC=C1)(C2=CN(CCN(C)C)C3=C2C=CC=N3)=O.Cl.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Schechter LE, et al. Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466. Neuropsychopharmacology. 2008 May;33(6):1323-35. ?

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